Incidence and Factors of Hypoglycemia in Perioperative Patients with Type 2 Diabetes Mellitus on Insulin Pump Therapy

Xiaohua Lu; Youshuang Zhu; Wane Zhao; Yan Liu; Xixi Luo; Yan Zhou

doi:doi:10.11648/j.ajns.20211002.13

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Incidence and Factors of Hypoglycemia in Perioperative Patients with Type 2 Diabetes Mellitus on Insulin Pump Therapy

Xiaohua Lu, Youshuang Zhu, Wane Zhao, Yan Liu, Xixi Luo, Yan Zhou

Published in American Journal of Nursing Science (Volume 10, Issue 2)

Received: 16 February 2021 Accepted: 13 March 2021 Published: 26 March 2021

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Abstract

Objective: To estimate the incidence of and identified factors associated with hypoglycemia among perioperative diabetes patients with insulin pump therapy. Methods: This was a retrospective cohort study of type 2 diabetes patients with insulin pump therapy newly received surgery. All patients were divided into hypoglycemia group and non-hypoglycemia group according to whether they experienced hypoglycemia. Information about clinical characteristics and treatments were collected and compared between two groups. We estimated the incidence of hypoglycemia, and identified factors associated with hypoglycemia by using multivariable logistic regression. Results: A total of 172 episodes of hypoglycemia were observed in 88 (39.8%) patients, among which, 146 (84.9%) were level 1 hypoglycemia (<3.9 mmol/L) and 26 (15.1%) were level 2 (< 3.0 mmol/L). No severe hypoglycemia (level 3) was reported in this study. Results from the multivariable logistic regression model found that diabetes patients with a longer duration of pump use were more likely to have hypoglycemia (AOR=1.09 with 95% CI=1.04-1.15). However, those diabetes patients who were with higher BMI and eGFR were less likely to have hypoglycemia (AOR=0.86 with 95% CI=0.76-0.98; AOR=0.86 with 95% CI=0.76-0.98, respectively). Conclusion: Perioperative diabetes patients with insulin pump therapy were prone to develop mild to moderate hypoglycemia. The long-term of receiving insulin pump therapy during the perioperative period, with lower BMI and eGFR, put type 2 diabetes at higher risks in hypoglycemia. It may help healthcare providers to screen hypoglycemia among type 2 diabetes patients with receiving long-term insulin pump therapy.

Published in	American Journal of Nursing Science (Volume 10, Issue 2)
DOI	10.11648/j.ajns.20211002.13
Page(s)	128-132
Creative Commons	This is an Open Access article, distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution and reproduction in any medium or format, provided the original work is properly cited.
Copyright	Copyright © The Author(s), 2024. Published by Science Publishing Group

Keywords

Continuous Subcutaneous Insulin Infusion, Insulin Pump Therapy, Perioperative Period, Type 2 Diabetes Mellitus, Hypoglycemia

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APA Style

Xiaohua Lu, Youshuang Zhu, Wane Zhao, Yan Liu, Xixi Luo, et al. (2021). Incidence and Factors of Hypoglycemia in Perioperative Patients with Type 2 Diabetes Mellitus on Insulin Pump Therapy. American Journal of Nursing Science, 10(2), 128-132. https://doi.org/10.11648/j.ajns.20211002.13

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ACS Style

Xiaohua Lu; Youshuang Zhu; Wane Zhao; Yan Liu; Xixi Luo, et al. Incidence and Factors of Hypoglycemia in Perioperative Patients with Type 2 Diabetes Mellitus on Insulin Pump Therapy. Am. J. Nurs. Sci. 2021, 10(2), 128-132. doi: 10.11648/j.ajns.20211002.13

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AMA Style

Xiaohua Lu, Youshuang Zhu, Wane Zhao, Yan Liu, Xixi Luo, et al. Incidence and Factors of Hypoglycemia in Perioperative Patients with Type 2 Diabetes Mellitus on Insulin Pump Therapy. Am J Nurs Sci. 2021;10(2):128-132. doi: 10.11648/j.ajns.20211002.13

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@article{10.11648/j.ajns.20211002.13,
  author = {Xiaohua Lu and Youshuang Zhu and Wane Zhao and Yan Liu and Xixi Luo and Yan Zhou},
  title = {Incidence and Factors of Hypoglycemia in Perioperative Patients with Type 2 Diabetes Mellitus on Insulin Pump Therapy},
  journal = {American Journal of Nursing Science},
  volume = {10},
  number = {2},
  pages = {128-132},
  doi = {10.11648/j.ajns.20211002.13},
  url = {https://doi.org/10.11648/j.ajns.20211002.13},
  eprint = {https://article.sciencepublishinggroup.com/pdf/10.11648.j.ajns.20211002.13},
  abstract = {Objective: To estimate the incidence of and identified factors associated with hypoglycemia among perioperative diabetes patients with insulin pump therapy. Methods: This was a retrospective cohort study of type 2 diabetes patients with insulin pump therapy newly received surgery. All patients were divided into hypoglycemia group and non-hypoglycemia group according to whether they experienced hypoglycemia. Information about clinical characteristics and treatments were collected and compared between two groups. We estimated the incidence of hypoglycemia, and identified factors associated with hypoglycemia by using multivariable logistic regression. Results: A total of 172 episodes of hypoglycemia were observed in 88 (39.8%) patients, among which, 146 (84.9%) were level 1 hypoglycemia (Conclusion: Perioperative diabetes patients with insulin pump therapy were prone to develop mild to moderate hypoglycemia. The long-term of receiving insulin pump therapy during the perioperative period, with lower BMI and eGFR, put type 2 diabetes at higher risks in hypoglycemia. It may help healthcare providers to screen hypoglycemia among type 2 diabetes patients with receiving long-term insulin pump therapy.},
 year = {2021}
}

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TY  - JOUR
T1  - Incidence and Factors of Hypoglycemia in Perioperative Patients with Type 2 Diabetes Mellitus on Insulin Pump Therapy
AU  - Xiaohua Lu
AU  - Youshuang Zhu
AU  - Wane Zhao
AU  - Yan Liu
AU  - Xixi Luo
AU  - Yan Zhou
Y1  - 2021/03/26
PY  - 2021
N1  - https://doi.org/10.11648/j.ajns.20211002.13
DO  - 10.11648/j.ajns.20211002.13
T2  - American Journal of Nursing Science
JF  - American Journal of Nursing Science
JO  - American Journal of Nursing Science
SP  - 128
EP  - 132
PB  - Science Publishing Group
SN  - 2328-5753
UR  - https://doi.org/10.11648/j.ajns.20211002.13
AB  - Objective: To estimate the incidence of and identified factors associated with hypoglycemia among perioperative diabetes patients with insulin pump therapy. Methods: This was a retrospective cohort study of type 2 diabetes patients with insulin pump therapy newly received surgery. All patients were divided into hypoglycemia group and non-hypoglycemia group according to whether they experienced hypoglycemia. Information about clinical characteristics and treatments were collected and compared between two groups. We estimated the incidence of hypoglycemia, and identified factors associated with hypoglycemia by using multivariable logistic regression. Results: A total of 172 episodes of hypoglycemia were observed in 88 (39.8%) patients, among which, 146 (84.9%) were level 1 hypoglycemia (Conclusion: Perioperative diabetes patients with insulin pump therapy were prone to develop mild to moderate hypoglycemia. The long-term of receiving insulin pump therapy during the perioperative period, with lower BMI and eGFR, put type 2 diabetes at higher risks in hypoglycemia. It may help healthcare providers to screen hypoglycemia among type 2 diabetes patients with receiving long-term insulin pump therapy.
VL  - 10
IS  - 2
ER  -

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Author Information

Xiaohua Lu

Department of Endocrinology, First Affiliated Hospital of Jinan University, Guangzhou, China
Youshuang Zhu

Department of Burn and Plastic Surgery and Intervention, First Affiliated Hospital of Jinan University, Guangzhou, China
Wane Zhao

Department of Endocrinology, First Affiliated Hospital of Jinan University, Guangzhou, China
Yan Liu

Department of Endocrinology, First Affiliated Hospital of Jinan University, Guangzhou, China
Xixi Luo

Department of Endocrinology, First Affiliated Hospital of Jinan University, Guangzhou, China
Yan Zhou

Department of Endocrinology, First Affiliated Hospital of Jinan University, Guangzhou, China

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Plain Text BibTeX RIS

APA Style

Xiaohua Lu, Youshuang Zhu, Wane Zhao, Yan Liu, Xixi Luo, et al. (2021). Incidence and Factors of Hypoglycemia in Perioperative Patients with Type 2 Diabetes Mellitus on Insulin Pump Therapy. American Journal of Nursing Science, 10(2), 128-132. https://doi.org/10.11648/j.ajns.20211002.13

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ACS Style

Xiaohua Lu; Youshuang Zhu; Wane Zhao; Yan Liu; Xixi Luo, et al. Incidence and Factors of Hypoglycemia in Perioperative Patients with Type 2 Diabetes Mellitus on Insulin Pump Therapy. Am. J. Nurs. Sci. 2021, 10(2), 128-132. doi: 10.11648/j.ajns.20211002.13

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AMA Style

Xiaohua Lu, Youshuang Zhu, Wane Zhao, Yan Liu, Xixi Luo, et al. Incidence and Factors of Hypoglycemia in Perioperative Patients with Type 2 Diabetes Mellitus on Insulin Pump Therapy. Am J Nurs Sci. 2021;10(2):128-132. doi: 10.11648/j.ajns.20211002.13

Copy | Download

@article{10.11648/j.ajns.20211002.13,
  author = {Xiaohua Lu and Youshuang Zhu and Wane Zhao and Yan Liu and Xixi Luo and Yan Zhou},
  title = {Incidence and Factors of Hypoglycemia in Perioperative Patients with Type 2 Diabetes Mellitus on Insulin Pump Therapy},
  journal = {American Journal of Nursing Science},
  volume = {10},
  number = {2},
  pages = {128-132},
  doi = {10.11648/j.ajns.20211002.13},
  url = {https://doi.org/10.11648/j.ajns.20211002.13},
  eprint = {https://article.sciencepublishinggroup.com/pdf/10.11648.j.ajns.20211002.13},
  abstract = {Objective: To estimate the incidence of and identified factors associated with hypoglycemia among perioperative diabetes patients with insulin pump therapy. Methods: This was a retrospective cohort study of type 2 diabetes patients with insulin pump therapy newly received surgery. All patients were divided into hypoglycemia group and non-hypoglycemia group according to whether they experienced hypoglycemia. Information about clinical characteristics and treatments were collected and compared between two groups. We estimated the incidence of hypoglycemia, and identified factors associated with hypoglycemia by using multivariable logistic regression. Results: A total of 172 episodes of hypoglycemia were observed in 88 (39.8%) patients, among which, 146 (84.9%) were level 1 hypoglycemia (Conclusion: Perioperative diabetes patients with insulin pump therapy were prone to develop mild to moderate hypoglycemia. The long-term of receiving insulin pump therapy during the perioperative period, with lower BMI and eGFR, put type 2 diabetes at higher risks in hypoglycemia. It may help healthcare providers to screen hypoglycemia among type 2 diabetes patients with receiving long-term insulin pump therapy.},
 year = {2021}
}

Copy | Download

TY  - JOUR
T1  - Incidence and Factors of Hypoglycemia in Perioperative Patients with Type 2 Diabetes Mellitus on Insulin Pump Therapy
AU  - Xiaohua Lu
AU  - Youshuang Zhu
AU  - Wane Zhao
AU  - Yan Liu
AU  - Xixi Luo
AU  - Yan Zhou
Y1  - 2021/03/26
PY  - 2021
N1  - https://doi.org/10.11648/j.ajns.20211002.13
DO  - 10.11648/j.ajns.20211002.13
T2  - American Journal of Nursing Science
JF  - American Journal of Nursing Science
JO  - American Journal of Nursing Science
SP  - 128
EP  - 132
PB  - Science Publishing Group
SN  - 2328-5753
UR  - https://doi.org/10.11648/j.ajns.20211002.13
AB  - Objective: To estimate the incidence of and identified factors associated with hypoglycemia among perioperative diabetes patients with insulin pump therapy. Methods: This was a retrospective cohort study of type 2 diabetes patients with insulin pump therapy newly received surgery. All patients were divided into hypoglycemia group and non-hypoglycemia group according to whether they experienced hypoglycemia. Information about clinical characteristics and treatments were collected and compared between two groups. We estimated the incidence of hypoglycemia, and identified factors associated with hypoglycemia by using multivariable logistic regression. Results: A total of 172 episodes of hypoglycemia were observed in 88 (39.8%) patients, among which, 146 (84.9%) were level 1 hypoglycemia (Conclusion: Perioperative diabetes patients with insulin pump therapy were prone to develop mild to moderate hypoglycemia. The long-term of receiving insulin pump therapy during the perioperative period, with lower BMI and eGFR, put type 2 diabetes at higher risks in hypoglycemia. It may help healthcare providers to screen hypoglycemia among type 2 diabetes patients with receiving long-term insulin pump therapy.
VL  - 10
IS  - 2
ER  -

Copy | Download